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İREM ÇOKSU.jpeg

PhD Stu. İrem Çoksu

She has graduated from the Department of Bioengineering at Yıldız Technical University in 2019. In July 2022, she completed her master's thesis on antimicrobial peptide-based, bacteria-targeted polymeric nanoparticles and received her master's degree in bioengineering. She is now a PhD student in the Bioengineering department at the Yildiz Technical University. Irem’s research interests are mainly drug delivery systems, but she has recently focused on solid phase peptide synthesis​.

Theses

  • Bachelor: 'Production of Ketoconazole-Loaded PLGA Nanoparticles and Investigation of Their Antifungal Activities', Yildiz Technical University, Department of Bioengineering, June 2019, Assoc. Prof. Dr. Serap DERMAN

  • Master: ‘Production of Targeted and Antibacterial Nanosystems and Evaluation of Their Biological Activity', Yildiz Technical University, Graduate School of Science and Engineering, Bioengineering Program, July 2022, Prof. Dr. Serap DERMAN

 

Articles

  1. Coksu I., Bozkurt Y., Akmayan I., Demirci H., Ozbek T., Derman S., ‘Ketoconazole-loading strategy to improve antifungal activity and overcome cytotoxicity on human renal proximal tubular epithelial cells’, (Submitted to Journal of Pharmaceutical Sciences/2022.)

  2. Acar T., Pelit Arayici P., Atabey T., Coksu I., Ucar B., Ozbek T., Derman S., ‘Host-Guest Interactions of Caffeic Acid Phenethyl Ester with β-Cyclodextrins: Improving the Antioxidant and Antimicrobial Properties of the Caffeic Acid Phenethyl Ester’, (Submitted to Supramolecular Chemistry/2022.)

  3. Ozdemir C., Gencer M., Coksu I., Ozbek T., Derman S., ‘A Novel Strategy for High Antimicrobial Activity: Green Synthesized Silver Nanoparticles Formulations from Galium aparine and Helichrysum arenarium’, (Submitted to Archives of Industrial Hygiene and Toxicology/2022.)

 

Projects

  1. Evaluation of Use of Holin Protein, Key Molecule of Lytic Bacteriophage K in S. aureus Lysis Mechanism, as a Biotechnological Tool, TUBITAK-1001, 122Z026, 01.11.2022/15.06.2025, Scholar (Continues)

  2. The Design of Novel Peptide-Based Antimicrobial Agents and Their In Vitro/In Vivo Investigation, TUBITAK-SDF International Bilateral Cooperation, 119S925, Scholar (06.2022/10.2022)

  3. Obtaining and In Vitro/In Vivo Evaluation of Nanoformulations Containing Recombinant Antigenic Proteins Against Brucellosis Disease, YTU-BAP, FBA-2022-4648, 20.01.2022/22.07.2024, Researcher (Continues).

  4. Production and Evaluation of Biological Activities of Antimicrobial Peptide-Based S aureus Targeted Functional Polymeric Nanoparticles, YTU-BAP, FKD-2021-4737, 10.11.2021/10.11.2022, Researcher (Continues).

  5. CAPE/Beta-Cyclodextrin Inclusion Complexes for Improving the Antimicrobial Activity of CAPE, YTU-BAP, FBA-2020-3830, 21.02.2020/21.02.2022, Researcher (Completed)

  6. Production of Ketoconazole-Loaded PLGA Nanoparticles and Investigation of Their Antifungal Activities. The Scientific and Technological Research Council of Turkey (TUBITAK) Program Code: 2209-B, 07.05.2018/10.05.2019, Manager (Completed).

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