Derman'S LAB
Functional Nano-Biomaterials and
Peptide Chemistry Research Group

Her research interests include solid phase peptide synthesis, bioconjugation reactions and nanoparticle systems. She has been working as a lecturer at Yıldız Technical University since 2018. She worked as a lecturer at Üsküdar University between 2017-2018. Completed her MSc degree in 2015 and the Ph.D degree in 2021 in Bioengineering Programme at Yildiz Technical University. She graduated from Yıldız Technical University, Faculty of Science and Letters, Department of Chemistry and Anadolu University, Department of Business Administration in 2012.
Thesis
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New Generation Protectıve Peptide Vaccine Models: Development Of Bioconjugates of Rabies Viral Peptides With Various Adjuvants" Yıldız Technical University, Graduate School of Natural and Applied Sciences, Bioengineering Department, January 2015.
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Development of Synthetic Polymers and Lipopolysaccharide Conjugates to Form a Vaccine Model for Q Fever and Structure Analysis, Yıldız Technical University, Graduate School of Natural and Applied Sciences, Bioengineering Department, June 2021.
Articles
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Ucar B., Acar T., Arayici Pelit P., Derman S. (2021). A nanotechnological approach in the current therapy of COVID-19: Model drug oseltamivir-phosphate loaded PLGA nanoparticles targeted with spike protein binder peptide of SARS-CoV-2. Nanotechnology, cilt.32(48).
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Arayici-Pelit P., Acar T., Ucar B., Karahan M., Derman S., Mustafaeva Z., Toman R. (2020). Development of Lipopolysaccharide-Polyoxidonium Complexes and Conjugates Against The Q Fever Disease For Application Purpose of Vaccine Prototype. Fresenius Environmental Bulletin. Cilt 29, No. 12A/2020 ss. 11349-11357.
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Topuzogullari M., Acar T., Arayici Pelit P., Uçar B., Uğurel E., Abamor E. Ş., Arasoğlu T., Turgut-Balık D., Derman S. (2020). An insight into the epitope-based peptide vaccine design strategy and studies against COVID-19, Turkish Journal Of Biology, cilt.44, ss.215-227.
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Acar T., Ucar B., Arayici Pelit P., Derman S., Mustafaeva Z., (2020). Covalent Conjugation and Characterization of the Ebola Nucleoprotein 421-430 Peptide with Polyacrylic Acid, Fresenius Environmental Bulletin, cilt.29, ss.5214-5219.
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Büyük N.İ., Arayici Pelit P., Derman S., Mustafaeva Z., Yücel S., (2020). Synthesis of Chitosan Nanoparticles for Controlled Release of Amiodarone, Indian Journal of Pharmaceutical Sciences, cilt. 82(1), ss.131-138.
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Beyoğlu, G., Araç, Ö., Taşkın, D., Arayıcı-Pelit, P., Kızılbey, K., Derman, S. (2020). Rutin Yüklü Kitosan Nanopartiküllerinin Sentezi, Karakterizasyonu ve Antioksidan Aktivitesinin Değerlendirilmesi, Eurasian J Bio Chem Sci, 3(2):93-99.
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Büyük N. İ., Arayıcı-Pelit, P., Derman S., Mustafaeva Z., Yücel S. (2020). An Optimization Study for Chitosan Nanoparticles: Synthesis and Characterization, Celal Bayar Üniversitesi Fen Bilimleri Dergisi, cilt.16, ss.119-127.
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Acar T., Arayici-Pelit P., Ucar B., Karahan M., Mustafaeva Z., (2019). Synthesis, Characterization and Lipophilicity Study of Brucella abortus' Immunogenic Peptide Sequence That Can Be Used in the Future Vaccination Studies, International Journal Of Peptide Research And Therapeutics, cilt.25, ss.911-918.
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Calman F., Arayici-Pelit P., Buyukbayraktar H. K., Karahan M., Mustafaeva Z., (2019). Katsarava R., Development of Vaccine Prototype Against Zika Virus Disease of Peptide-Loaded PLGA Nanoparticles and Evaluation of Cytotoxicity. International Journal Of Peptide Research And Therapeutics, cilt.25, ss.1057-1063.
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Arayici-Pelit P., Acar T., Ucar B., Karahan M., Arslan B. A., Mustafaeva Z. (2019), Rabies Virus 31D Peptide-[P(VP-co-AA)] Conjugates: Synthesis, Characterization and Cytotoxicity Evaluation. ChemıstrySelect, cilt.4, ss.9483-9487.
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Uçar B., Acar T., Arayici-Pelit P., Demirkol M. O., Mustafaeva Z.,(2018). A New Radıo-Theranostıc Agent Candidate: Synthesis and Analysis of (Adh-1)C-EDTA Conjugate. Fresenius Environmental Bulletin, cilt.27, ss.4751-4758.
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Uçar B., Acar T., Arayici-Pelit P. Mustafaeva Z., Demirkol M. O. (2018). [Ga-68]Ga-AntiCAD1: Radiosynthesis and First Imaging Study on Rats. Kafkas Ünıversitesi Veteriner Fakultesi Dergisi, cilt.24, ss.531-538.
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Arayici-Pelit P., Acar T., Maharramov, M. A., Karahan, M., Mustafaeva, Z., (2017). Synthesis and Characterization Of Bioconjugates Of Antigenic Rabies Virus Peptide Epitope With Polyacrylic Acid (PAA). Fresenius Enviromental Bulletin, 26(4): 2753-2759.
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Vural, P., Karahan, M., Arayici-Pelit, P., Mustafaeva, Z., (2017). Radiation induced formation of poly (N- isopropyl acrylamide)-bovine serum albumin covalent conjugates and their immunogenicity. Bulgarian Chemical Communications, 49(3): 557 – 561.
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Ergin, B., Arayıcı-Pelit, P., Mustafaeva, Z., Mamedov, B., (2017). Fighter Molecules Againist To Cancer – Peptide Vaccines. Sigma J Eng & Nat Sci 35 (2), 203-211.
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Can, F., Arayıcı-Pelit, P., Karahan, M., Mustafaeva, Z., Mamedov, B., (2016). Current Approaches towards Zika Virus, Biotechnologia Acta, 9(4):7-13, https://doi.org/10.15407/biotech9.04.007.
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Yılmaz, F. E., Arayıcı-Pelit, P., Maharramov, M. A., Mustafaeva, Z. (2016). New Generation Vaccine Approaches Against The Sheep Pox Disease’’, Biotechnologia Acta, 9(6):7-15, https://doi.org/10.15407/biotech9.06.007.
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Arayıcı-Pelit, P., Acar T., Karahan M., Akdeste M. Z., (2016). Viral Hastalıklara Karşı Sentetik Peptid Aşılarının Geliştirilmesi İçin Yeni Bir Yaklaşım, Sigma J Eng & Nat Sci 7 (2), 193-204.
Books & Book Chapters
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Uçar B., Acar T., Pelit Arayici P., Şen M., Derman S., Mustafaeva Z., "Synthesis and Applications of Synthetic Peptides", in: Peptide Synthesis, Dr. Jaya T. Varkey, Eds., ISBN: 978-1-83968-258-2, eBook (PDF) ISBN: 978-1-83968-259-9, IntechOpen, London, pp.1-25, 2019. https://doi.org/10.5772/intechopen.85486 (book chapter).
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Acar T., Arayıcı-Pelit, P., Karahan M., Akdeste M.Z., Post-translational Modifications’, 2015. ‘Applications of Molecular Genetics in Personalized Medicine’, Korkut Ulucan (Editor), OMICS Group Incorporation, (e-book chapter).
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Pelit, P., Acar, T., Karahan, M., Transcription and translation, 2014., ‘Applications of Molecular Genetics in Personalized Medicine’, Korkut Ulucan (Editor), OMICS Group Incorporation, (e-book chapter).
Projects
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Vaccine Prototype and Diagnostic Kit Application Purpose Development of Lipopolysaccharide-Biopolymer Complex and Conjugates Against Q Fever Disease, Tübitak-SAS International Collaboration Project, Scholarship.
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A New Approach in the Treatment of Helicobacter Pylori Infection and Helicobacter Pylori Mediated Gastric Cancer: Investigation of In Vitro and In Vivo Therapeutic Efficacy of PLGA Nanoparticles Containing Cape-Silver-Peptide Triple Complexes, TUBITAK 1001 project no 122Z255, 2022-2025, Researcher.
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Evaluation of Use of Holin Protein, Key Molecule of Lytic Bacteriophage K in S. aureus Lysis Mechanism, as a Biotechnological Tool, TUBITAK 1001 project no 122Z026, 2022-2025, Researcher.
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Production and Evaluation of Biological Activities of Antimicrobial Peptide-Based S aureus Targeted Functional Polymeric Nanoparticles, 2021-Continued. YTU-BAP, FKD-2021-4737 KADEP Project, Project Coordinator.
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Development of Antigen-Loaded Polymeric Nanoparticular Vaccine Candidates Against Breast Cancer 2021- Ongoing, YTU-BAP, G. Research Project, Researcher.
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Establishment of Turkey's Antigenic Peptide/Protein Libraries for Use in COVID-19 Vaccine, Production of Specific Antigenic Peptide/Proteins and Obtaining Immune Response Results as Vaccine Formulations, Ministry of Health-TUSEB, 2020-2021, Researcher.
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CAPE-Beta Cyclodextrin Inclusion Complexes for Improvement of Antimicrobial Activity of CAPE, YTU-BAP, FBA-2020-3830, Researcher.
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Development of Synthetic Polymers Conjugates with Lipopolysaccharides and Structure Investigation to Create a Vaccine Model Against Q Fever Disease- (DOP), 2016-07-04-DOP05, Researcher
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Development of New Generation Peptide Vaccine Models Against Ebola Virus Disease, YTU Scientific Research Project (KAP), 2015-2017, 2015-07-04-KAP01, Researcher.
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Establishment of Chemical-Controlled Drug Release Systems with Insulin, YTU Scientific Research Project (GEP) 2013-2015, Researcher
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Development of New Generation Peptide Vaccine Models Protecting From Viral Infections, YTU Scientific Research Project (KAP) 2013-2015, Researcher.